Endocrine Abstracts

Introduction: The aim of this study was to examine the relationship between serum calcium levels and renal function before and after curative parathyroidectomy (PTX) in patients with primary hyperparathyroidism (PHPT).Objective and methods: A retrospective evaluation of 48 patient cases, corresponding ICD-10 code E21.0, was carried out, including demographic data and such biochemical markers as serum calcium, creatinine and estimated glomerular filtratio...

Clinical response to metformin is highly variable in type 2 diabetes (T2D) patients highlighting the need for identification of genetic components affecting the efficiency of metformin therapy. Aim of this study was to evaluate the role of systematically selected tagSNPs from genomic regions coding for six organic cation transporters implicated in transport of metformin with respect to the short-term efficiency. The study involved 102 drug naïve newly diagnosed T2D patien...